Scientists say controlled CO2 bursts may clear Alzheimer's proteins

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Scientists say controlled CO2 bursts may clear Alzheimer's proteins
The study could open the door to eventual clinical trials that test efficacy, benefits, and safety. ©Image Credit: Unsplash / engin akyurt

Alzheimer's research has taken another interesting turn, this time uses short pulses of carbon dioxide inhaled through a face mask. The data shows that it could help clear out the toxic proteins that are linked to Alzheimer's disease.

CO2-enriched air could help flush out toxins

Imagine being able to put on a mask, inhale CO2-enriched air, and potentially help reduce the symptoms of Alzheimer's disease. Well, that's exactly what a recent study looked at.

The 2025 study took place at the University of New Mexico School of Medicine and The Mind Research Network, led by Dr. Sephira Ryman.

The study focused on intermittent exposure to inhaled CO2-enriched air and how it worked to move the cerebrospinal fluid, which then flushed out toxic proteins such as tau.

Researchers saw improved clearance of tau protein from the participants' brains and higher levels of amyloid beta in their bloodstream.

Short sessions with pulses of CO2 were used

The researchers used short sessions of around 30 minutes in total, delivering short bursts of CO2 through a mask.

When the participant inhaled the CO2, their blood vessels in their brain dilated and constricted. It worked like a pump so that fluid moved easily through the brain tissue.

“This dilation and constriction essentially serves as a pump that clears waste from the brain,” said Ryman.

Results recently shared at an international conference

The results of the study were shared earlier in the month at the Alzheimer's Association International Conference (AAIC) in London.

In the presentation, the study was described as small and preliminary, with a need for larger clinical trials. Clinical trials will be able to assess things like efficacy, long-term safety, and benefits for cognitive decline.

There are an estimated 7.4 million Americans age 65 and older who have Alzheimer's dementia.

Working towards a cure

Any breakthrough in Alzheimer's disease is welcome, as researchers work towards finding a cure. If you're decades away from your golden years, the idea of Alzheimer's being treatable is pretty positive.

Source: The Dallas Express